Prevalence and associated risk factors for HIV, hepatitis B, hepatitis C, syphilis and HSV-2 among injecting drug users from three cities in Afghanistan

MOPE217 – Poster Exhibition

Prevalence and associated risk factors for HIV, hepatitis B, hepatitis C, syphilis and HSV-2 among injecting drug users from three cities in Afghanistan

H. Ruisenor-Escudero, I. Familiar-Lopez

Johns Hopkins Bloomberg School of Public Health, Baltimore, United States

Background: There is a lack of robust epidemiologic evidence on HIV and sexually transmitted diseases among injecting drug users (IDU) in Afghanistan. This study seeks to generate information to develop and implement surveillance systems and public health programs to tackle the spread of these epidemics. Methods: IDUs were recruited during 2009 using Respondent Driven Sampling in Herat, Kabul and Mezar-i-Sharif, Afghanistan. After providing informed consent, a questionnaire was applied, followed by pre-test counseling, rapid testing for HIV, Hepatitis B Virus (HBV), Hepatitis C Virus (HCV), Syphilis and Herpes Simplex Virus-2 (HSV-2) and post-test counseling. logistic regression models were used to explore associations. Results: A total of 548 IDUs were recruited: 286 (52.2%) in Kabul, 160 (29.2%) in Herat and 102 (18.6%) in Mezar-i-Sharif. Highest HIV prevalence was in Herat (18.4%), followed by Kabul (3.1%), and Mezar-i-Sharif (1%) . Herat had the highest HCV prevalence (55.7%), while Mezar-i-Sharif had the highest syphilis and HSV-2 prevalence (16.7% and 20.6%, respectively). In the final adjusted model, factors associated with an increased risk of HIV infection were: living in Herat (OR=), >3years injecting drugs (OR=7.15, 95% CI=1.29-39.6) ever being in prison (OR=9.43, 95% CI=1.14-78), and HCV seropositive (OR=15.7, 95% CI=3.38-72.5). In the multivariate model for HCV, risk of infection was associated with time injecting drugs (OR=2.3, 95% CI=1.5-3.7 for 1-3 years of injecting drug use, and OR=5.36, 95% CI=3.01-9.54 for those reporting more than 3 years) and ever being in prison (OR=1.4, 95% CI=1.8-2.1). For HSV, an increase odds of infection was observed in Kabul (OR=4.6, 95% CI=1.1-19.5) and Mezar-i-Sharif (OR=8.7, 95% CI=2.0-37.8) when compared to Herat. Conclusions: Our results contribute to the understanding of these epidemics among IDUs, and will serve to strengthen and enhance a national response towards the control and prevention of HIV, HCV, HBV, syphilis and HSV-2 in Afghanistan.

Advertisements

Posted on July 23, 2012, in Uncategorized. Bookmark the permalink. Comments Off on Prevalence and associated risk factors for HIV, hepatitis B, hepatitis C, syphilis and HSV-2 among injecting drug users from three cities in Afghanistan.

Comments are closed.

%d bloggers like this: